TargetMol

HPI 1

Product Code:
 
TAR-T22089
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22089-1mg1mg£102.00
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TAR-T22089-2mg2mg£115.00
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TAR-T22089-5mg5mg£145.00
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TAR-T22089-1mL1 mL * 10 mM (in DMSO)£158.00
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TAR-T22089-10mg10mg£181.00
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TAR-T22089-25mg25mg£254.00
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Quantity:
TAR-T22089-50mg50mg£345.00
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TAR-T22089-100mg100mg£470.00
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Quantity:
TAR-T22089-500mg500mg£938.00
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This product comes from: United States.
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Further Information

Bioactivity:
HPI 1 is a hedgehog (Hh) signaling inhibitor. Inhibits Sonic hedgehog (Shh)-, SAG- and Gli-induced Hh pathway activation in Shh-LIGHT2 cells (IC50 values are 1.5, 1.5, 4, and 6 μM for Shh-, SAG-, Gli2- and Gli1-induced activation).
CAS:
599150-20-6
Formula:
C27H29NO6
Molecular Weight:
463.53
Pathway:
GPCR/G Protein; Stem Cells
Purity:
0.98
SMILES:
COCCOC(=O)C1=C(C)NC2=C(C1c1cccc(O)c1)C(=O)CC(C2)c1ccccc1OC
Target:
Hedgehog/Smoothened

References

1. Gavrish E, et al. In vitro and in vivo activities of HPi1, a selective antimicrobial against Helicobacter pylori. Antimicrob Agents Chemother. 2014 Jun;58(6):3255-60.