TargetMol

Org 25543 hydrochloride

Product Code:
 
TAR-T22126
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22126-1mg1mg£148.00
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TAR-T22126-2mg2mg£205.00
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TAR-T22126-5mg5mg£245.00
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TAR-T22126-10mg10mg£324.00
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TAR-T22126-25mg25mg£495.00
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TAR-T22126-50mg50mg£687.00
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Quantity:
TAR-T22126-100mg100mg£938.00
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This product comes from: United States.
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Further Information

Bioactivity:
Org 25543 hydrochloride is a potent and selective glycine transporter type 2 (GlyT2) inhibitor (IC50 = 16 nM for hGlyT2). Displays no activity at GlyT1 or 56 other common biological targets (? 100 μM), in a glycine uptake assay in CHO cells.
CAS:
495076-64-7
Formula:
C24H33ClN2O4
Molecular Weight:
448.99
Pathway:
Neuroscience
Purity:
0.9934
SMILES:
Cl.COc1cc(cc(OC)c1OCc1ccccc1)C(=O)NCC1(CCCC1)N(C)C
Target:
GlyT

References

1. W L Caulfield, et al.The first potent and selective inhibitors of the glycine transporter type 2.J Med Chem . 2001 Aug 16;44(17):2679-82.