TargetMol

AZ9482

Product Code:
 
TAR-T22264
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22264-1mg1mg£112.00
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TAR-T22264-5mg5mg£177.00
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TAR-T22264-1mL1 mL * 10 mM (in DMSO)£185.00
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TAR-T22264-10mg10mg£243.00
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TAR-T22264-25mg25mg£399.00
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TAR-T22264-50mg50mg£548.00
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Quantity:
TAR-T22264-100mg100mg£766.00
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This product comes from: United States.
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Further Information

Bioactivity:
AZ9482 is a selective and potent inhibitor of PARP featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent activity of centrosome declustering with EC50 of < 18 nM in HeLa cells.
CAS:
1825345-33-2
Formula:
C26H22N6O2
Molecular Weight:
450.502
Pathway:
Chromatin/Epigenetic; DNA Damage/DNA Repair
Purity:
0.9929
SMILES:
O=C(N1CCN(CC1)c1ncccc1C#N)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1
Target:
PARP

References

1. Howard R T , Hemsley P , Petteruti P , et al. Structure-Guided Design and In-Cell Target Profiling of a Cell-Active Target Engagement Probe for PARP Inhibitors[J]. ACS Chemical Biology, 2020, XXXX(XXX).