TargetMol

NLX-204 hydrochloride?2170405-10-2 free base?

Product Code:
 
TAR-T22379L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T22379L-1mg1mg£143.00
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TAR-T22379L-5mg5mg£219.00
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TAR-T22379L-1mL1 mL * 10 mM (in DMSO)£241.00
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TAR-T22379L-10mg10mg£283.00
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TAR-T22379L-25mg25mg£454.00
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TAR-T22379L-50mg50mg£617.00
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Quantity:
TAR-T22379L-100mg100mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
NLX-204 hydrochloride is a potent and selective ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor agonist(pKi = 10.19).
CAS:
T22379L
Formula:
C20H23Cl2F2N3O2
Molecular Weight:
409.13
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.9987
SMILES:
[H]Cl.O=C(C1=CC=C(F)C(Cl)=C1)N2CCC(CNCCOC3=NC=CC=C3)(F)CC2
Target:
5-HT Receptor

References

1. Sniecikowska, Joanna, G?uch-Lutwin, Monika, Bucki, Adam,et al. Novel aryloxyethyl derivatives of 1-(1-benzoylpiperidin-4-yl)methanamine as the Extracellular Regulated Kinases 1/2 (ERK1/2) phosphorylation-preferring serotonin 5 HT1A receptor biased agonists with robust antidepressant-like activity[J]. Journal of Medicinal Chemistry, 2019.