TargetMol

Adenosine Kinase Inhibitor (hydrate)

Product Code:
 
TAR-T22554
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22554-1mg1mg£135.00
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TAR-T22554-5mg5mg£322.00
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TAR-T22554-10mg10mg£384.00
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Further Information

Bioactivity:
Adenosine kinase is the key metabolizing enzyme regulating cellular adenosine concentrations. Inhibition of adenosine kinase can selectively enhance the protective actions of adenosine during tissue trauma without producing the nonspecific effects associated with the systemic administration of adenosine receptor agonists (IC50: 1.7 nM in cell-free assays).
CAS:
T22554
Formula:
C22H19BrN6O?0.4H2O
Molecular Weight:
470.5
Purity:
0.98
SMILES:
BrC1=CC=CC(C2=CC(C3=CN=C(N4CCOCC4)C=C3)=NC5=C2C(N)=NC=N5)=C1.O

References

1. Buang Y.? Dietary adenine alleviates fatty liver induced by orotic acid. Indo. J. Chem. 2010; 10 (3): 363 - 369. 2. M?dis K, Ger D, Nagy N, Szoleczky P, T?th ZD and Szab? C.? Cytoprotective effects of adenosine and inosine in an in vitro model of acute tubular necrosis. Br J Pharmacol. 2009 Nov; 158(6): 1565?8.