TargetMol

Tezacaftor

Product Code:
 
TAR-T2263
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2263-1mg1mg£98.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2263-2mg2mg£109.00
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Quantity:
TAR-T2263-5mg5mg£131.00
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Quantity:
TAR-T2263-1mL1 mL * 10 mM (in DMSO)£143.00
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Quantity:
TAR-T2263-10mg10mg£171.00
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Quantity:
TAR-T2263-25mg25mg£250.00
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Quantity:
TAR-T2263-50mg50mg£360.00
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Quantity:
TAR-T2263-100mg100mg£497.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
VX-661 is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.
CAS:
1152311-62-0
Formula:
C26H27F3N2O6
Molecular Weight:
520.505
Pathway:
Membrane transporter/Ion channel; Autophagy
Purity:
0.99
SMILES:
CC(C)(CO)c1cc2cc(NC(=O)C3(CC3)c3ccc4OC(F)(F)Oc4c3)c(F)cc2n1C[C@@H](O)CO
Target:
CFTR; Autophagy

References

1. Vertex to host investor conference 2. Jarosz-Griffiths H H, Scambler T, Wong C H, et al. Different CFTR modulator combinations downregulate inflammation differently in cystic fibrosis[J]. eLife. 2020, 9: e54556.