TargetMol

TLR3-IN-1

Product Code:
 
TAR-T22698
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22698-1mg1mg£109.00
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TAR-T22698-2mg2mg£125.00
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TAR-T22698-5mg5mg£164.00
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TAR-T22698-1mL1 mL * 10 mM (in DMSO)£173.00
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TAR-T22698-10mg10mg£229.00
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TAR-T22698-25mg25mg£406.00
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Quantity:
TAR-T22698-50mg50mg£573.00
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TAR-T22698-100mg100mg£785.00
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Quantity:
TAR-T22698-500mg500mg£1,508.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
CU CPT 4a is a selective TLR3 inhibitor (IC50: 3.44 μM in RAW 264.7 cells). It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the production of TNF-α and IL-1β in whole cells.
CAS:
1279713-77-7
Formula:
C18H13ClFNO3S
Molecular Weight:
377.81
Pathway:
Immunology/Inflammation
Purity:
0.9777
SMILES:
[H][C@](Cc1ccccc1)(N=C(/O)c1sc2cc(F)ccc2c1Cl)C(O)=O
Target:
TLR

References

1. Cheng K , Wang X , Yin H . Small-Molecule Inhibitors of the TLR3/dsRNA Complex[J]. Journal of the American Chemical Society, 2011, 133(11):p.3764-3767.