TargetMol

MEDICA16

Product Code:
 
TAR-T22967
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22967-1mg1mg£103.00
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TAR-T22967-5mg5mg£148.00
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TAR-T22967-1mL1 mL * 10 mM (in DMSO)£174.00
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TAR-T22967-10mg10mg£189.00
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TAR-T22967-25mg25mg£322.00
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TAR-T22967-50mg50mg£503.00
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TAR-T22967-100mg100mg£695.00
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TAR-T22967-500mg500mg£1,372.00
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Further Information

Bioactivity:
MEDICA16 is a selective agonist for GPR40 as well as a partial agonist for GPR120. MEDICA16, an ATP-citrate lyase inhibitor, significantly reduces intracellular TG content in gastrocnemius muscle with an increase in insulin sensitivity.
CAS:
87272-20-6
Formula:
C20H38O4
Molecular Weight:
342.52
Pathway:
Metabolism; Endocrinology/Hormones; ; GPCR/G Protein
Purity:
0.9913
SMILES:
CC(C)(CCCCCCCCCCC(C)(C)CC(O)=O)CC(O)=O
Target:
GPR; ATP Citrate Lyase

References

1. Hara T, Hirasawa A, Sun Q, et al. Novel selective ligands for free fatty acid receptors GPR120 and GPR40. Naunyn Schmiedebergs Arch Pharmacol. 2009;380(3):247-255. 2. Atkinson LL, et al. MEDICA 16 inhibits hepatic acetyl-CoA carboxylase and reduces plasma triacylglycerol levels in insulin-resistant JCR: LA-cp rats. Diabetes. 2002;51(5):1548-1555.