TargetMol

ML337

Product Code:
 
TAR-T23003
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23003-1mg1mg£106.00
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TAR-T23003-5mg5mg£149.00
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TAR-T23003-1mL1 mL * 10 mM (in DMSO)£164.00
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TAR-T23003-10mg10mg£209.00
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TAR-T23003-25mg25mg£362.00
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TAR-T23003-50mg50mg£507.00
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TAR-T23003-100mg100mg£699.00
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Further Information

Bioactivity:
ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.
CAS:
1443118-44-2
Formula:
C21H20FNO3
Molecular Weight:
353.39
Pathway:
Neuroscience
Purity:
0.9909
SMILES:
C(=O)(C1=C(F)C=C(C#CC2=CC=C(OC)C=C2)C=C1)N3C[C@H](O)CCC3
Target:
GluR

References

1. Wenthur CJ, et, al. Discovery of (R)-(2-fluoro-4-((-4-methoxyphenyl)ethynyl)phenyl) (3-hydroxypiperidin-1-yl)methanone (ML337), an mGlu3 selective and CNS penetrant negative allosteric modulator (NAM). J Med Chem. 2013 Jun 27; 56(12): 5208-12.