TargetMol

RS 67333 hydrochloride

Product Code:
 
TAR-T23265
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23265-1mg1mg£95.00
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TAR-T23265-5mg5mg£128.00
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TAR-T23265-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T23265-10mg10mg£168.00
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TAR-T23265-25mg25mg£302.00
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TAR-T23265-50mg50mg£434.00
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TAR-T23265-100mg100mg£605.00
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Further Information

Bioactivity:
RS 67333 hydrochloride is a potent and selective 5-HT4 receptor (5-HT4R) partial agonist with a pKi of 8.7 in guinea-pig striatum. RS 67333 hydrochloride exhibits lower affinities at several other receptors including 5-HT1A, 5-HT1D, 5-HT2A, 5-HT2C, dopamine D1, D2 and muscarinic M1-M3 receptors. RS 67333 hydrochloride shows neuroprotective effects, and can be used for Alzheimer's disease research.
CAS:
168986-60-5
Formula:
C19H30Cl2N2O2
Molecular Weight:
389.36
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.9878
SMILES:
Cl.O=C(C=1C=C(Cl)C(N)=CC1OC)CCC2CCN(CCCC)CC2
Target:
5-HT Receptor

References

1. R M Eglen, et al. Pharmacological characterization of two novel and potent 5-HT4 receptor agonists, RS 67333 and RS 67506, in vitro and in vivo. Br J Pharmacol. 1995 Aug;115(8):1387-92.