TargetMol

SF 11

Product Code:
 
TAR-T23349
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23349-1mg1mg£111.00
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TAR-T23349-2mg2mg£130.00
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TAR-T23349-5mg5mg£168.00
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TAR-T23349-10mg10mg£229.00
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TAR-T23349-25mg25mg£389.00
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TAR-T23349-50mg50mg£630.00
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Quantity:
TAR-T23349-100mg100mg£938.00
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Quantity:
TAR-T23349-200mg200mg£1,235.00
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Quantity:
TAR-T23349-500mg500mg£1,805.00
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Quantity:
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Further Information

Bioactivity:
SF 11 is a potent and brain penetrant neuropeptide Y Y2 receptor antagonist with IC50 of 199 nM. Antidepressant-like activity
CAS:
443292-81-7
Formula:
C27H30N2O2S
Molecular Weight:
446.6
Purity:
0.9854
SMILES:
S=C(NC1=CC=C(OCC)C=C1)N2CCC(CC2)C(O)(C=3C=CC=CC3)C=4C=CC=CC4

References

1. Domin H, et al. Characterization of the Brain Penetrant Neuropeptide Y Y2 Receptor Antagonist SF-11. ACS Chem Neurosci. 2019;10(8):3454-3463. 2. Brothers SP, et al. Selective and brain penetrant neuropeptide y y2 receptor antagonists discovered by whole-cell high-throughput screening. Mol Pharmacol. 2010;77(1):46-57.