TargetMol

TCS 1105

Product Code:
 
TAR-T23444
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23444-1mg1mg£111.00
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TAR-T23444-5mg5mg£149.00
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TAR-T23444-10mg10mg£187.00
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TAR-T23444-25mg25mg£260.00
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TAR-T23444-50mg50mg£350.00
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Quantity:
TAR-T23444-100mg100mg£486.00
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Quantity:
TAR-T23444-500mg500mg£1,002.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
TCS 1105 is a GABAA benzodiazepine receptor (BZR) ligand. TCS 1105 blocks Sema3A induced axonal growth cones collapse. TCS 1105 reduces anxiety-like behavior and enhances offensive behavior and social dominance in mice.
CAS:
185391-33-7
Formula:
C17H13FN2O2
Molecular Weight:
296.3
Purity:
0.9855
SMILES:
Fc1ccc(CNC(=O)C(=O)c2c[nH]c3ccccc23)cc1

References

1. Xu J, et al. Anesthetics disrupt growth cone guidance cue sensing through actions on the GABAA ?2 receptor mediated by the immature chloride gradient. Neurotoxicol Teratol. 2019 Jul-Aug;74:106812. 2. van der Kooij MA, et al. GABAA receptors in the ventral tegmental area control the outcome of a social competition in rats. Neuropharmacology. 2018 Aug;138:275-281.