TargetMol

Z-VEID-FMK

Product Code:
 
TAR-T23555
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23555-1mg1mg£156.00
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TAR-T23555-5mg5mg£297.00
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TAR-T23555-10mg10mg£446.00
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TAR-T23555-25mg25mg£670.00
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This product comes from: United States.
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Further Information

Bioactivity:
When compared to other caspase inhibitors, Z-DRHD-FMK inhibited caspase 6 activity more effectively than the general caspase inhibitor of Z-Val-Ala-Asp (OMe)-fluoromethy ketone (Z-VAD-FMK) or the caspase 6 inhibitor Z-Val-Glu(Ome)-Ile-Asp(OMe)-fluoromethyl ketone. However, it was less effective in inhibiting TNFα-induced apoptosis than Z-VAD-FMK or Z-VEID-FMK, presumably.
CAS:
T23555
Formula:
C31H45FN4O10
Molecular Weight:
652.71
Purity:
0.98
SMILES:
CCC(C)C(C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)C(CCC(=O)OC)NC(=O)C(C(C)C)NC(=O)OCC1=CC=CC=C1

References

1. Su, Kuan-Wei, et al. Repurposing cabozantinib with therapeutic potential in KIT-driven t (8; 21) acute myeloid leukaemias. Cancer Gene Therapy . (2021): 1-14.