TargetMol

Inecalcitol

Product Code:
 
TAR-T24166
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24166-1mg1mg£502.00
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TAR-T24166-2mg2mg£693.00
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TAR-T24166-5mg5mg£1,026.00
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TAR-T24166-1mL1 mL * 10 mM (in DMSO)£1,267.00
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TAR-T24166-10mg10mg£1,348.00
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TAR-T24166-25mg25mg£1,990.00
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Quantity:
TAR-T24166-50mg50mg£2,657.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Inecalcitol is the growth inhibitor of human breast cancer cells. Inecalcitol is a unique vitamin D3 analog with Kd of 0.53 nM.
CAS:
163217-09-2
Formula:
C26H40O3
Molecular Weight:
400.603
Pathway:
Apoptosis
Purity:
0.98
SMILES:
C[C@H](CC#CC(C)(C)O)[C@H]1CC[C@@H]2C(CCC[C@]12C)=CC=C1C[C@@H](O)C[C@H](O)C1
Target:
Apoptosis

References

1. Ryoko Okamoto, et al. Inecalcitol, an analog of 1?,25(OH)(2) D(3) , induces growth arrest of androgen-dependent prostate cancer cells. Int J Cancer. 2012 May 15;130(10):2464-73. 2. Murray A, et al. Vitamin D receptor as a target for breast cancer therapy. Endocr Relat Cancer. 2017 Apr;24(4):181-195. 3. Suares A, et al. The proapoptotic protein Bim is up regulated by 1?,25-dihydroxyvitamin D3 and its receptor agonist in endothelial cells and transformed by viral GPCR associated to Kaposi sarcoma. Steroids. 2015 Oct;102:85-91. 4. Van Belle TL, et al. 1,25-Dihydroxyvitamin D3 and its analog TX527 promote a stable regulatory T cell phenotype in T cells from type 1 diabetes patients. PLoS One. 2014 Oct 3;9(10):e109194.