TargetMol

Amitivir

Product Code:
 
TAR-T26619
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26619-1mg1mg£177.00
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TAR-T26619-1mL1 mL * 10 mM (in DMSO)£242.00
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TAR-T26619-5mg5mg£313.00
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TAR-T26619-10mg10mg£430.00
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TAR-T26619-25mg25mg£663.00
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TAR-T26619-50mg50mg£863.00
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TAR-T26619-100mg100mg£1,179.00
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TAR-T26619-500mg500mg£2,311.00
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This product comes from: United States.
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Further Information

Bioactivity:
Amitivir is an inosine monophosphate dehydrogenase inhibitor. Amitivir inhibits the replication of dividing MDCK cells. Amitivir was associated with asymptomatic rises in serum uric acid levels and was ineffective in modifying the virologic or clinical course of experimental influenza A (H1N1) virus infection.
CAS:
111393-84-1
Formula:
C3H2N4S
Molecular Weight:
126.14
Pathway:
Microbiology/Virology;
Purity:
0.95
SMILES:
N#CNC1=NN=CS1
Target:
Influenza Virus

References

1. Herman J L , Chay S H . Quantitative Whole-body Autoradiography in Pregnant Rabbits to Determine Fetal Exposure of Potential Teratogenic Compounds[J]. Journal of Pharmacological & Toxicological Methods, 1998, 39(1):29. 2. Bonate PL, Peyton A. Uptake and biodisposition of 2-ylcyanamide-1,3,4-thiadiazole (LY217896) by red blood cells. Biopharm Drug Dispos. 1995 Mar;16(2):151-67. PubMed PMID: 7780048. 3. Hayden FG, Tunkel AR, Treanor JJ, Betts RF, Allerheiligen S, Harris J. Oral LY217896 for prevention of experimental influenza A virus infection and illness in humans. Antimicrob Agents Chemother. 1994 May;38(5):1178-8PubMed PMID: 8067760; PubMed Central PMCID: PMC188174. 4. Ehlhardt WJ, Wheeler WJ, Breau AP, Chay SH, Birch GM. Biotransformation of the antiviral agent 1,3,4-thiadiazol-2-ylcyanamide (LY217896) and characteristics of a mesoionic ribose metabolite. Drug Metab Dispos. 1993 Jan-Feb;21(1):162-70. PubMed PMID: 8095212.