TargetMol

ENMD-1068 HCl

Product Code:
 
TAR-T27267
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27267-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T27267-10mg10mg£111.00
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TAR-T27267-25mg25mg£140.00
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TAR-T27267-50mg50mg£181.00
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This product comes from: United States.
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Further Information

Bioactivity:
ENMD-1068 is a PAR-2 antagonist. ENMD-1068 inhibits the development of endometriosis in a mouse model.
CAS:
789488-77-3
Formula:
C15H30ClN3O2
Molecular Weight:
319.87
Pathway:
GPCR/G Protein
Purity:
0.98
SMILES:
Cl.CC(C)CC(=O)N1CCN(CC1)C(=O)CCCCCN
Target:
Protease-activated Receptor

References

1. Ibrahim Sulaiman, et al. Molecularly targeted therapies for asthma: Current development, challenges and potential clinical translation. Pulm Pharmacol Ther. 2016 Oct;40:52-68. 2. Hyosun Jang, et al. Skin pH Is the Master Switch of Kallikrein 5-Mediated Skin Barrier Destruction in a Murine Atopic Dermatitis Model. J Invest Dermatol. 2016 Jan;136(1):127-35. 3. Ahmed Nadeem, et al. Proteinase activated receptor-2-mediated dual oxidase-2 up-regulation is involved in enhanced airway reactivity and inflammation in a mouse model of allergic asthma. Immunology. 2015 Jul;145(3):391-403. 4. Nadeem A, Alharbi NO, Vliagoftis H, Tyagi M, Ahmad SF, Sayed-Ahmed MM. Proteinase activated receptor-2-mediated dual oxidase-2 up-regulation is involved in enhanced airway reactivity and inflammation in a mouse model of allergic asthma. Immunology. 2015 Jul;145(3):391-403. doi: 10.1111/imm.12453. PubMed PMID: 25684443; PubMed Central PMCID: PMC4479538.