TargetMol

Ganaplacide phosphate

Product Code:
 
TAR-T27400L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T27400L-1mg1mg£227.00
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TAR-T27400L-5mg5mg£422.00
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TAR-T27400L-1mL1 mL * 10 mM (in DMSO)£506.00
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TAR-T27400L-10mg10mg£589.00
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TAR-T27400L-25mg25mg£863.00
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TAR-T27400L-50mg50mg£1,179.00
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TAR-T27400L-100mg100mg£1,564.00
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TAR-T27400L-500mg500mg£3,058.00
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This product comes from: United States.
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Further Information

Bioactivity:
Ganaplacide phosphate exerts multi-stage antimalarial activity against Plasmodium symptomatic asexual blood-stage infections, and is able to prevent transmission and block infection in animal models.
CAS:
T27400L
Formula:
C22H26F2N5O5P
Molecular Weight:
509.44
Purity:
0.9969
SMILES:
CC1(C2=NC(C3=CC=C(F)C=C3)=C(NC4=CC=C(F)C=C4)N2CCN1C(CN)=O)C.OP(O)(O)=O

References

1. Koller R, Mombo-Ngoma G, Grobusch MP. The early preclinical and clinical development of ganaplacide (KAF156), a novel antimalarial compound. Expert Opin Investig Drugs. 2018 Oct;27(10):803-810. 2. LaMonte GM, et al. Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway. Nat Commun. 2020 Apr 14;11(1):1780.