TargetMol

Suprafenacine

Product Code:
 
TAR-T28886
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28886-1mg1mg£148.00
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TAR-T28886-5mg5mg£248.00
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TAR-T28886-1mL1 mL * 10 mM (in DMSO)£253.00
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TAR-T28886-10mg10mg£322.00
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TAR-T28886-25mg25mg£523.00
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TAR-T28886-50mg50mg£706.00
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TAR-T28886-100mg100mg£970.00
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TAR-T28886-500mg500mg£1,878.00
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This product comes from: United States.
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Further Information

Bioactivity:
Suprafenacine is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2/M phase. Suprafenacine binds to microtubules and inhibits aggregation at the colchicine junction. Suprafenacine is selective for cancer cells, including drug-resistant cancer cells.
CAS:
1477482-50-0
Formula:
C16H18N4O
Molecular Weight:
282.347
Pathway:
Cytoskeletal Signaling
Purity:
0.9823
SMILES:
Cc1ccc(C=NNC(=O)c2n[nH]c3CCCCc23)cc1
Target:
Microtubule Associated

References

1. Choi BH, Chattopadhaya S, Thanh le N, Feng L, Nguyen QT, Lim CB, Harikishore A, Nanga RP, Bharatham N, Zhao Y, Liu X, Yoon HS. Suprafenacine, an indazole-hydrazide agent, targets cancer cells through microtubule destabilization. PLoS One. 2014 Oct 29;9(10):e110955.