TargetMol

Triiodothyronine Sulfate

Product Code:
 
TAR-T29011
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T29011-1mg1mg£278.00
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TAR-T29011-5mg5mg£494.00
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TAR-T29011-10mg10mg£707.00
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TAR-T29011-25mg25mg£1,214.00
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TAR-T29011-50mg50mg£1,786.00
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Quantity:
TAR-T29011-100mg100mg£2,636.00
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This product comes from: United States.
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Further Information

Bioactivity:
Triiodothyronine Sulfate is a prodrug to the Conventional Hormone Therapy of Hypothyroidism. Triiodothyronine sulfate is the main metabolite of thyroid hormone triiodothyronine (T3). Triiodothyronine is an active form of thyroid hormone bind to β1 thyroid hormone receptor (TRβ1), and activates its activity[1][2].
CAS:
31135-55-4
Formula:
C15H11I3NNaO7S
Molecular Weight:
753.02
Pathway:
Endocrinology/Hormones; Metabolism
Purity:
0.98
SMILES:
[Na+].NC(Cc1cc(I)c(Oc2ccc(OS(O)(=O)=O)c(I)c2)c(I)c1)C([O-])=O
Target:
Thyroid hormone receptor(THR); Endogenous Metabolite

References

1. J S LoPresti, et al. 3,5,3'-Triiodothyronine (T3) sulfate: a major metabolite in T3 metabolism in man. J Clin Endocrinol Metab. 1994 Mar;78(3):688-92. 2. Lin KH, et al. Stimulation of proliferation by 3,3',5-triiodo-L-thyronine in poorly differentiated human hepatocarcinoma cells overexpressing beta 1 thyroid hormone receptor. Cancer Lett. 1994 Oct 14;85(2):189-94. 3. Bhat MK, et al. Conformational changes of human beta 1 thyroid hormone receptor induced by binding of 3,3',5-triiodo-L-thyronine. Biochem Biophys Res Commun. 1993 Aug 31;195(1):385-92. 4. Bernus I, Mitchell AM, Manley SW, Mortimer RH. Uptake of L-triiodothyronine sulphate by human choriocarcinoma cell line, JAr. Placenta. 1999 Mar-Apr;20(2-3):161-5. PubMed PMID: 10195736.