TargetMol

Momordin Ic

Product Code:
 
TAR-T3410
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T3410-1mL1 mL * 10 mM (in DMSO)£135.00
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TAR-T3410-20mg20mg£135.00
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Further Information

Bioactivity:
Momordin Ic might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction involving the MAPK and PI3K-mediated iNOS and HO-1 pathways. Also, Momordin Ic accelerates gastrointestinal transit partially by stimulating synthesis of 5-HT to act through 5-HT(2), which, in turn, increases synthesis of prostaglandins.
CAS:
96990-18-0
Formula:
C41H64O13
Molecular Weight:
764.95
Pathway:
Apoptosis; MAPK; PI3K/Akt/mTOR signaling
Purity:
0.9961
SMILES:
CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H]([C@H](O)[C@@H](O[C@H]7OC[C@H](O)[C@@H](O)[C@@H]7O)[C@@H]6O)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O
Target:
Apoptosis; MAPK; PI3K

References

Li Y, et al. Eur J Pharmacol. 2000 Mar 24;392(1-2):71-7. Wang J, et al. Apoptosis. 2013 Jun;18(6):751-65. Matsuda H, et al. J Pharmacol Exp Ther. 1999 May;289(2):729-34. Kim NY, et al. J Med Food. 2005 Summer;8(2):177-83.