TargetMol

ζ-Stat

Product Code:
 
TAR-T35407
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T35407-1mg1mg£166.00
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TAR-T35407-5mg5mg£309.00
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TAR-T35407-10mg10mg£450.00
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TAR-T35407-25mg25mg£695.00
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Quantity:
TAR-T35407-50mg50mg£946.00
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Quantity:
TAR-T35407-100mg100mg£1,243.00
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Quantity:
TAR-T35407-500mg500mg£2,424.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ζ-Stat (NSC37044) is a specific and atypical PKC-ζ inhibitor, with an IC50 of 5 μM. ζ-Stat can reduce melanoma cell lines proliferation and induce apoptosis, and has antitumor activity in vitro[1][2].
CAS:
3316-02-7
Formula:
C10H8O10S3
Molecular Weight:
384.36
Pathway:
Chromatin/Epigenetic; Cytoskeletal Signaling
Purity:
0.98
SMILES:
N/A
Target:
PKC

References

Islam SMA, et, al. Atypical Protein Kinase-C inhibitors exhibit a synergistic effect in facilitating DNA damaging effect of 5-fluorouracil in colorectal cancer cells. Biomed Pharmacother. 2020 Jan; 121:109665. Ratnayake WS, et, al. Oncogenic PKC-? activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-? and PKC-? specific inhibitors. Cell Adh Migr. 2018; 12(5):447-463.