TargetMol

19-O-Acetylchaetoglobosin A

Product Code:
 
TAR-T35609
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35609-1mg1mg£185.00
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TAR-T35609-5mg5mg£418.00
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Further Information

Bioactivity:
19-O-Acetylchaetoglobosin A is a fungal metabolite originally isolated fromC. globosumthat has actin polymerization inhibitory and cytotoxic activities.1,2It inhibits actin polymerization in a cell-free assay when used at a concentration of 2 μM.219-O-Acetylchaetoglobosin A (3.2, 10, and 32 μg/ml) is cytotoxic to HeLa cervical cancer cells.1
CAS:
50939-69-0
Formula:
C34H38N2O6
Molecular Weight:
570.686
Purity:
0.98
SMILES:
C[C@H]1C2[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@]22[C@@H](C=C/C[C@H](C)C=C(C)/[C@@H](OC(C)=O)C(=O)C=C/C2=O)[C@@H]2O[C@]12C

References

Umeda, M., Ohtsubo, K., Saito, M., et al.Cytotoxicity of new cytochalasans from Chaetomium globosumExperientia31(4)435-438(1975) Sekita, S., Yoshihira, K., Natori, S., et al.Structure-activity relationship of thirty-nine cytochalasans observed in the effects on cellular structures and cellular events and on actin polymerization in vitroJ. Pharmacobiodyn.8(11)906-916(1985)