TargetMol

C2 L-threo Ceramide (d18:1/2:0)

Product Code:
 
TAR-T35927
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35927-1mg1mg£294.00
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Further Information

Bioactivity:
C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 μM, however, this efflux is 50% less than that stimulated by C2 ceramide . C2 L-threo Ceramide inhibits IL-4 production by 17% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. It also induces cell cycle arrest in the G0/G1 phase and a 7-fold increase in sphingosine accumulation as well as inhibits growth of HL-60 leukemia cells.
CAS:
143615-69-4
Formula:
C20H39NO3
Molecular Weight:
341.536
Purity:
0.98
SMILES:
CCCCCCCCCCCCCC=C[C@H](O)[C@H](CO)NC(C)=O