TargetMol

PAR2 (1-6) (mouse, rat)

Product Code:
 
TAR-T36531
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T36531-1mg1mg£111.00
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Quantity:
TAR-T36531-5mg5mg£266.00
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TAR-T36531-10mg10mg£419.00
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Quantity:
TAR-T36531-25mg25mg£838.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
PAR2 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse and rat PAR2. It also corresponds to residues 39-44 and 37-42 of the mouse and rat full-length sequences, respectively. PAR2 (1-6) induces relaxation in precontracted rat arteries in a concentration-dependent manner, an effect that can be reduced by the nitric oxide synthase inhibitor L-NNA . It inhibits keratinocyte growth in the presence and absence of growth factors. PAR2 (1-6) inhibits LPS-induced pulmonary neutrophil influx and increases in matrix metalloproteinase-2 (MMP-2) activity in mice.
CAS:
164081-25-8
Formula:
C29H55N9O8
Molecular Weight:
657.8
Purity:
0.98
SMILES:
[H]N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@]([C@H](CC)C)([H])C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O