TargetMol

9-hydroxy Stearic Acid

Product Code:
 
TAR-T37067
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T37067-1mg1mg£102.00
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TAR-T37067-5mg5mg£209.00
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TAR-T37067-10mg10mg£309.00
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TAR-T37067-25mg25mg£466.00
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TAR-T37067-50mg50mg£647.00
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Quantity:
TAR-T37067-100mg100mg£863.00
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This product comes from: United States.
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Further Information

Bioactivity:
9-hydroxy Stearic acid is a hydroxy fatty acid and an active metabolite of 9-PAHSA .1,2It is formed from 9-PAHSA by liver and pancreatic carboxyl ester lipases.29-hydroxy Stearic acid (5 μM) inhibits histone deacetylase 1 (HDAC1) in HT-29 colon cancer cell lysates.3It inhibits the proliferation of, and induces cell cycle arrest at the G0/G1phase in, HT-29 cells when used at a concentration of 100 μM.1
CAS:
3384-24-5
Formula:
C18H36O3
Molecular Weight:
300.5
Pathway:
DNA Damage/DNA Repair|Chromatin/Epigenetic
Purity:
0.98
SMILES:
OC(CCCCCCCC(O)CCCCCCCCC)=O
Target:
HDAC

References

Calonghi N, et al. 9-Hydroxystearic acid upregulates p21(WAF1) in HT29 cancer cells. Biochem Biophys Res Commun. 2004;314(1):138-14 Calonghi N, et al. Histone deacetylase 1: a target of 9-hydroxystearic acid in the inhibition of cell growth in human colon cancer. J Lipid Res. 2005;46(8):1596-1603. Kolar MJ, et al. Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase. Biochemistry. 2016;55(33):4636-4641.