TargetMol

1-Palmitoyl Lysophosphatidic Acid

Product Code:
 
TAR-T37282
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T37282-10mg10mgEnquire
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TAR-T37282-25mg25mgEnquire
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TAR-T37282-1mg1mg£414.00
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Further Information

Bioactivity:
1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of at least five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. Additionally, 1-palmitoyl LPA enhances the action of β-lactam antibiotics (ampicillin, piperacillin, and ceftazidime) on various strains of P. aeruginosa, a pathogen associated with pulmonary disease and pneumonia, via binding both Ca2+ and Mg2+.
CAS:
22002-85-3
Formula:
C19H39O7P
Molecular Weight:
410.5
Pathway:
Microbiology/Virology
Purity:
0.98
SMILES:
CCCCCCCCCCCCCCCC(OC[C@@H](O)COP(O)(O)=O)=O
Target:
Antibacterial

References

Krogfelt KA, et al. Specific phospholipids enhance the activity of beta-lactam antibiotics against Pseudomonas aeruginosa. J Antimicrob Chemother. 2000 Sep;46(3):377-84.