TargetMol

6-O-desmethyl Donepezil

Product Code:
 
TAR-T37360
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T37360-1mg1mg£234.00
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Quantity:
TAR-T37360-5mg5mg£784.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
6-O-desmethyl Donepezil is an active metabolite of the acetylcholinesterase inhibitor donepezil . It is formed through dealkylation by the cytochrome P450 (CYP) isoform CYP2D6. It inhibits human ether a go-go (hERG) channels (IC50 = 1.5 μM in HEK293 cells expressing hERG).
CAS:
120013-56-1
Formula:
C23H27NO3
Molecular Weight:
365.473
Purity:
0.98
SMILES:
COc1cc2CC(CC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1O