TargetMol

4-Methylumbelliferyl 2-sulfamino-2-deoxy- α-D-Glucopyranoside (sodium salt)

Product Code:
 
TAR-T37568
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T37568-1mg1mg£187.00
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Further Information

Bioactivity:
4-Methylumbelliferyl 2-sulfamino-2-deoxy-α-D-Glucopyranoside (4-MU-α-GlcNS) is a fluorogenic substrate of heparin sulphamidase. Heparin sulphamidase cleaves 4-MU-α-GlcNS to yield 4-MU-α-GlcNH2, which is then cleaved by α-glucosaminidase to release the fluorescent product 4-MU, which displays an emission maxima of 445-454 nm. The excitation maxima for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively. 4-MU-α-GlcNS has been used to quantify heparin sulphamidase deficiencies associated with Mucopolisaccaridosis IIIA and other lysosomal disorders.
CAS:
460085-45-4
Formula:
C16H18NNaO10S
Molecular Weight:
439.37
Purity:
0.98
SMILES:
[Na+].Cc1cc(=O)oc2cc(OC3OC(CO)C(O)C(O)C3NS([O-])(=O)=O)ccc12