Tryptoquivaline D

Product Code:

TAR-T37584

Product Group:

Inhibitors and Activators

Supplier:

TargetMol

Regulatory Status:

RUO

Shipping:

cool pack

Storage:

-20℃

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Code	Size	Price

TAR-T37584-1mg

1mg

£786.00

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Further Information

Bioactivity:

Tryptoquivaline D is a fungal metabolite that has been found inNeosartorya siamensisand has anticancer activity.1,2It induces nuclear chromatin condensation, a marker of apoptosis, in HCT116 colon and HepG2 liver cancer cells when used at a concentration of 150 μM.1Tryptoquivaline D (1-100 μM), alone or in combination with doxorubicin , reduces the viability of A549 lung cancer cells.2

CAS:

60676-56-4

Formula:

C28H28N4O7

Molecular Weight:

532.553

Purity:

0.98

SMILES:

CC(C)[C@@H](OC(C)=O)c1nc2ccccc2c(=O)n1[C@H]1C[C@]2(OC1=O)[C@H]1N(O)[C@H](C)C(=O)N1c1ccccc21

Documents

References

Prata-Sena, M., Ramos, A.A., Buttachon, S., et al.Cytotoxic activity of secondary metabolites from marine-derived fungus Neosartorya siamensis in human cancer cellsPhytother. Res.30(11)1862-1871(2016) Ramos, A.A., Castro-Carvalho , B., Prata-Sena, M., et al.Can marine-derived fungus Neosartorya siamensis KUFA 0017 extract and its secondary metabolites enhance antitumor activity of doxorubicin? An in vitro survey unveils interactions against lung cancer cellsEnviron. Toxicol.35(4)507-517(2020)