TargetMol

17-trifluoromethylphenyl trinor Prostaglandin F2 α

Product Code:
 
TAR-T37946
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T37946-1mg1mg£129.00
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TAR-T37946-5mg5mg£345.00
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TAR-T37946-10mg10mg£560.00
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Further Information

Bioactivity:
A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most potent FP receptor agonists. 17-trifluoromethylphenyl trinor PGF2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl trinor PGF2α would act very much like the free acid of travoprost. 17-phenyl trinor PGF2α is a potent luteolytic and abortifacient, with a potency equal to or greater than fluprostenol and cloprostenol.
CAS:
221246-34-0
Formula:
C24H31O5F3
Molecular Weight:
456.5
Purity:
0.98
SMILES:
O[C@@H]1[C@H](C/C=CCCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCC2=CC(C(F)(F)F)=CC=C2)[C@H](O)C1