TargetMol

Kocurin

Product Code:
 
TAR-T38009
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38009-1mg1mg£268.00
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Further Information

Bioactivity:
Kocurin is a thiazolyl peptide originally isolated fromK. palustrisand has antibiotic activity.1It is active against methicillin-resistantS. aureus(MRSA; MIC = 0.25 μg/ml), as well asB. subtilisandE. faeciumin a solid agar test when used at a concentration of 8 μg/ml. Kocurin is also active againstE. faecium,E. faecalis,S. epidermidis, and clinical isolates of vancomycin-resistant enterococci (MICs = 0.004-1.025 μg/ml).2
CAS:
1374772-61-8
Formula:
C69H66N18O13S5
Molecular Weight:
1515.7
Purity:
0.98
SMILES:
[H][C@]1(CCCN1C([C@H](CC2=CC=C(O)C=C2)NC([C@]3([H])CSC([C@H](CC4=CC=CC=C4)NC5=O)=N3)=O)=O)C6=NC(C7=NC(C8=NC(C9=NC(C(NC(C(N[C@@H](C)C(N%10[C@H](C(NC(C(NC(C(N)=O)=C)=O)=C)=O)CCC%10)=O)=O)=C)=O)=CS9)=CC=C8C%11=NC(C(N[C@@H](CC(N)=O)C%12=NC5=CS%12)=O)=C(C)O%11)=CS7)=CS6

References

Mahajan, G., Thomas, B., Parab, R., et al.In vitro and in vivo activities of antibiotic PM181104Antimicrob. Agents Chemother.57(11)5315-5319(2013) Martin, J., da S. Sousa, T., Crespo, G., et al.Kocurin, the true structure of PM181104, an anti-methicillin-resistant Staphylococcus aureus (MRSA) thiazolyl peptide from the marine-derived bacterium Kocuria palustrisMar. Drugs11(2)387-398(2013)