TargetMol

N-Acetyl lysyltyrosylcysteine amide

Product Code:
 
TAR-T38063
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38063-1mg1mg£128.00
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Quantity:
TAR-T38063-5mg5mg£217.00
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Quantity:
TAR-T38063-10mg10mg£322.00
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TAR-T38063-25mg25mg£495.00
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Quantity:
TAR-T38063-50mg50mg£675.00
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Quantity:
TAR-T38063-100mg100mg£863.00
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Quantity:
TAR-T38063-500mg500mg£1,661.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
N-Acetyl lysyltyrosylcysteine amide is a potent, reversible, specific, and non-toxic tripeptide inhibitor of myeloperoxidase (MPO). N-Acetyl lysyltyrosylcysteine amide effectively inhibits MPO generation of toxic oxidants in vivo. N-Acetyl lysyltyrosylcysteine amide reduces neuronal damage and preserves brain tissue and neurological function in the stroked brain. N-Acetyl lysyltyrosylcysteine amide inhibits MPO-dependent hypochlorous acid (HOCl) generation, protein nitration, and LDL oxidation[1][2].
CAS:
1287585-40-3
Formula:
C20H31N5O5S
Molecular Weight:
453.56
Pathway:
Metabolism
Purity:
0.98
SMILES:
SC[C@@H](C(N)=O)NC([C@H](CC1=CC=C(O)C=C1)NC([C@H](CCCCN)NC(C)=O)=O)=O
Target:
Glutathione Peroxidase

References

Zhang H, et al. N-acetyl lysyltyrosylcysteine amide inhibits myeloperoxidase, a novel tripeptide inhibitor. J Lipid Res. 2013;54(11):3016-3029. Yu G, et al. Inhibition of myeloperoxidase oxidant production by N-acetyl lysyltyrosylcysteine amide reduces brain damage in a murine model of stroke [published correction appears in J Neuroinflammation. 2016;13(1):166]. J Neuroinflammation. 2016;13(1):119. Published 2016 May 24.