TargetMol

ML-148

Product Code:
 
TAR-T38163
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38163-1mg1mg£115.00
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TAR-T38163-5mg5mg£222.00
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TAR-T38163-1mL1 mL * 10 mM (in DMSO)£230.00
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TAR-T38163-10mg10mg£309.00
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TAR-T38163-25mg25mg£502.00
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TAR-T38163-50mg50mg£693.00
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TAR-T38163-100mg100mg£938.00
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TAR-T38163-500mg500mg£1,813.00
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Further Information

Bioactivity:
ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM). ML-148 can be used to profile across a panel of related dehydrogenase or reductase enzymes and in studies about prostaglandin-signaling pathways.
CAS:
451496-96-1
Formula:
C20H21N3O
Molecular Weight:
319.4
Pathway:
Metabolism
Purity:
0.98
SMILES:
O=C(C=1C=CC2=C(N=CN2C3=CC=CC(=C3)C)C1)N4CCCCC4
Target:
Dehydrogenase

References

Niesen FH, et al. High-affinity inhibitors of human NAD-dependent 15-hydroxyprostaglandin dehydrogenase: mechanisms of inhibition and structure-activity relationships. PLoS One. 2010 Nov 2;5(11):e13719.