TargetMol

BE-24566B

Product Code:
 
TAR-T38167
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38167-1mg1mg£413.00
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Further Information

Bioactivity:
BE-24566B is a polyketide fungal metabolite originally isolated fromS. violaceusniger.1It is active againstB. subtilis,B. cereus,S. aureus,M. luteus,E. faecalis, andS. thermophilus(MICs = 1.56, 1.56, 1.56, 1.56, 3.13, and 3.13 μg/ml, respectively). BE-24566B is an endothelin (ET) receptor antagonist (IC50s = 11 and 3.9 μM for ETAand ETBreceptors, respectively).2
CAS:
149466-04-6
Formula:
C27H24O7
Molecular Weight:
460.5
Purity:
0.98
SMILES:
O=C(C(C(O)=CC(O)=C1)=C1C2(C)C)C(C2=C3)=C(O)C4=C3C[C@]5(C)OC6=CC(O)=CC(C)=C6[C@H]4O5

References

Lam, Y.K.T., Hensens, O., Helms, G., et al.L-755,805, a new polyketide endothelin binding inhibitor from an actinomyceteTetrahedron Lett.36(12)2013-2016(1995) Kojiri, K., Nakajima, S., Fuse, A., et al.BE-24566B, a new antibiotic produced by Streptomyces violaceusnigerJ. Antibiot. (Tokyo)48(12)1506-1508(1995)