TargetMol

Prostaglandin E3

Product Code:
 
TAR-T38194
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38194-1mg1mg£2,090.00
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Further Information

Bioactivity:
Prostaglandin E3 (PGE3) is formed via the cyclooxygenase (COX) metabolism of eicosapentaenoic acid. [1] In human ocular tissue, it comprises 2.4% of the COX products formed. [1] When applied to the eyes of a rabbit, a 1 µg dose of PGE3 decreases intraocular pressure from 21 mmHg to about 17 mmHg.[2]
CAS:
802-31-3
Formula:
C20H30O5
Molecular Weight:
350.455
Purity:
0.98
SMILES:
CCC=C/C[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CC=C/CCCC(O)=O

References

Kulkarni, P.S., and Srinivasan, B.D. Prostaglandins E3 and D3 lower intraocular pressure. Investigative Ophthalmology & Visual Science 26, 1178-1182 (1985). Kulkarni, P.S., and Srinivasan, B.D. Eicosapentaenoic acid metabolism in human and rabbit anterior uvea. Prostaglandins 31(6), 1159-1164 (1986).