TargetMol

L-Sepiapterin

Product Code:
 
TAR-T38250
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38250-5mg5mg£850.00
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TAR-T38250-50mg50mg£1,661.00
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Quantity:
TAR-T38250-100mg100mg£2,079.00
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Further Information

Bioactivity:
L-Sepiapterin (Sepiapterin) is a precursor of the endothelial nitric oxide synthase (eNOS) cofactor tetrahydrobiopterin (BH4). L-Sepiapterin improves endothelial dysfunction in small mesenteric arteries from db/db mice, and induces angiogenesis. L-Sepiapterin inhibits cell proliferation and migration of ovarian cancer cells via down-regulation of p70S6K-dependent VEGFR-2 expression[1][2].
CAS:
17094-01-8
Formula:
C9H11N5O3
Molecular Weight:
237.22
Purity:
0.98
SMILES:
O=C1NC(N)=NC2=C1N=C(C([C@@H](O)C)=O)CN2

References

Cho YR, et al. Sepiapterin inhibits cell proliferation and migration of ovarian cancer cells via down-regulation of p70S6K-dependent VEGFR-2 expression. Oncol Rep. 2011;26(4):861?867. Pannirselvam M, et al. Chronic oral supplementation with sepiapterin prevents endothelial dysfunction and oxidative stress in small mesenteric arteries from diabetic (db/db) mice. Br J Pharmacol. 2003;140(4):701?706.