TargetMol

Triclabendazole sulfoxide

Product Code:
 
TAR-T38400
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38400-1mg1mg£131.00
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TAR-T38400-5mg5mg£193.00
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TAR-T38400-1mL1 mL * 10 mM (in DMSO)£211.00
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TAR-T38400-10mg10mg£254.00
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TAR-T38400-25mg25mg£401.00
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TAR-T38400-50mg50mg£563.00
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TAR-T38400-100mg100mg£771.00
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TAR-T38400-500mg500mg£1,500.00
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This product comes from: United States.
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Further Information

Bioactivity:
Triclabendazole sulfoxide is a main plasma metabolite of Triclabendazole. Triclabendazole sulfoxide inhibits membrane transporter ABCG2/BCRP and exhibits anti-parasite effects.
CAS:
100648-13-3
Formula:
C14H9Cl3N2O2S
Molecular Weight:
375.65
Pathway:
Microbiology/Virology; Membrane transporter/Ion channel
Purity:
0.98
SMILES:
CS(=O)c1nc2cc(Oc3cccc(Cl)c3Cl)c(Cl)cc2[nH]1
Target:
BCRP; Parasite

References

Barrera B, et, al. The anthelmintic triclabendazole and its metabolites inhibit the membrane transporter ABCG2/BCRP. Antimicrob Agents Chemother. 2012 Jul;56(7):3535-43. Robinson MW, et, al. The comparative metabolism of triclabendazole sulphoxide by triclabendazole-susceptible and triclabendazole-resistant Fasciola hepatica. Parasitol Res. 2004 Feb;92(3):205-10.