TargetMol

AKN-028

Product Code:
 
TAR-T38562
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38562-1mg1mg£103.00
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TAR-T38562-5mg5mg£142.00
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TAR-T38562-10mg10mg£192.00
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TAR-T38562-25mg25mg£321.00
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TAR-T38562-50mg50mg£464.00
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Quantity:
TAR-T38562-100mg100mg£645.00
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This product comes from: United States.
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Further Information

Bioactivity:
AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation.
CAS:
1175017-90-9
Formula:
C17H14N6
Molecular Weight:
302.33
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.98
SMILES:
NC1=NC=C(N=C1NC1=CC=C2NC=CC2=C1)C1=CC=NC=C1
Target:
FLT

References

A Eriksson, et al. The Novel Tyrosine Kinase Inhibitor AKN-028 Has Significant Antileukemic Activity in Cell Lines and Primary Cultures of Acute Myeloid Leukemia. Blood Cancer J. 2012 Aug 3;2(8):e81.