TargetMol

Linerixibat

Product Code:
 
TAR-T3978
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3978-1mg1mg£132.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3978-2mg2mg£166.00
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TAR-T3978-5mg5mg£249.00
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TAR-T3978-1mL1 mL * 10 mM (in DMSO)£286.00
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TAR-T3978-10mg10mg£369.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3978-25mg25mg£576.00
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Quantity:
TAR-T3978-50mg50mg£790.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
GSK2330672 is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ? 3 nM). It can lower glucose in an animal model of type 2 diabetes and shows excellent developability properties.
CAS:
1345982-69-5
Formula:
C28H38N2O7S
Molecular Weight:
546.68
Pathway:
Microbiology/Virology
Purity:
0.9957
SMILES:
CCCC[C@@]1(CS(=O)(=O)c2cc(c(cc2[C@H](N1)c1ccccc1)OC)CNC(CC(=O)O)CC(=O)O)CC
Target:
HBV

References

Wu Y, et al. Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes. J Med Chem. 2013 Jun 27;56(12):5094-114. Nunez DJ, et al. Glucose and lipid effects of the ileal apical sodium-dependent bile acid transporter inhibitor GSK2330672: double-blind randomized trials with type 2 diabetes subjects taking metformin. Diabetes Obes Metab. 2016 Jul;18(7):654-62.