TargetMol

TRV120056 acetate

Product Code:
 
TAR-T40508L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-T40508L-1mg1mg£111.00
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TAR-T40508L-5mg5mg£140.00
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TAR-T40508L-10mg10mg£181.00
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TAR-T40508L-1mL1 mL * 10 mM (in DMSO)£217.00
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TAR-T40508L-25mg25mg£269.00
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TAR-T40508L-50mg50mg£367.00
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Quantity:
TAR-T40508L-100mg100mg£516.00
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This product comes from: United States.
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Further Information

Bioactivity:
TRV120056 acetate is a Gq-biased agonist with 10-fold greater molecular efficiency on AT1R-Gq fusion proteins than AT1R-βarr2 fusion proteins.
CAS:
0
Formula:
C45H69N13O14
Molecular Weight:
1016.11
Purity:
0.9916
SMILES:
O=C(N(CCC1)[C@@H]1C(NCC(O)=O)=O)[C@@H](NC([C@@]([C@H](C)CC)([H])NC([C@@H](NC([C@@H](C(C)C)NC([C@@H](CCCNC(N)=N)NC([C@@H](N)CC(O)=O)=O)=O)=O)CC2=CC=C(O)C=C2)=O)=O)CC3=CNC=N3.CC(O)=O

References

Rajagopal S, et, al. Quantifying ligand bias at seven-transmembrane receptors. Mol Pharmacol. 2011 Sep;80(3):367-77. Strachan RT, et, al. Divergent transducer-specific molecular efficacies generate biased agonism at a G protein-coupled receptor (GPCR). J Biol Chem. 2014 May 16; 289(20): 14211-24.