TargetMol

Bisdionin C

Product Code:
 
TAR-T40863
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T40863-1mg1mg£116.00
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TAR-T40863-5mg5mg£181.00
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TAR-T40863-10mg10mg£246.00
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TAR-T40863-25mg25mg£389.00
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TAR-T40863-50mg50mg£550.00
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TAR-T40863-100mg100mg£768.00
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Quantity:
TAR-T40863-500mg500mg£1,492.00
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Further Information

Bioactivity:
Bisdionin C is a potent inhibitor of GH18 chitinase with an IC50 of 0.2 μM for A. fumigatus ChiB1. Bisdionin C inhibits human macrophage chitotriosidase(HCHT, IC50 = 8.3 μM) and acidic mammalian chitinase (AMCase, IC50 = 3.4 μM).
CAS:
74857-22-0
Formula:
C17H20N8O4
Molecular Weight:
400.399
Pathway:
Microbiology/Virology
Purity:
0.9802
SMILES:
Cn1cnc2n(C)c(=O)n(CCCn3c(=O)n(C)c4ncn(C)c4c3=O)c(=O)c12
Target:
Antibacterial

References

Sch?ttelkopf AW, et al. Bisdionin C-a rationally designed, submicromolar inhibitor of family 18 chitinases. ACS Med Chem Lett. 2011;2(6):428-432. Published 2011 Mar 23.