TargetMol

IRAK4-IN-1

Product Code:
 
TAR-T4140
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4140-1mg1mg£122.00
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TAR-T4140-5mg5mg£195.00
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TAR-T4140-10mg10mg£262.00
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TAR-T4140-25mg25mg£462.00
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TAR-T4140-50mg50mg£642.00
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TAR-T4140-100mg100mg£863.00
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Quantity:
TAR-T4140-500mg500mg£1,661.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.
CAS:
1820787-94-7
Formula:
C19H23N5O
Molecular Weight:
337.427
Pathway:
Immunology/Inflammation; NF-κb
Purity:
0.9974
SMILES:
N#Cc1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N3CCOCC3)c2c1
Target:
IRAK

References

Smith GF, et al. Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2721-2726.