TargetMol

CY-09

Product Code:
 
TAR-T4164
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4164-1mg1mg£108.00
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TAR-T4164-5mg5mg£125.00
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TAR-T4164-1mL1 mL * 10 mM (in DMSO)£131.00
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TAR-T4164-10mg10mg£165.00
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TAR-T4164-25mg25mg£269.00
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TAR-T4164-50mg50mg£385.00
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Quantity:
TAR-T4164-100mg100mg£544.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
CY-09 is an NLRP3 inhibitor.
CAS:
1073612-91-5
Formula:
C19H12F3NO3S2
Molecular Weight:
423.42
Pathway:
Immunology/Inflammation; NF-κb
Purity:
1
SMILES:
OC(=O)c1ccc(C=C2/SC(=S)N(Cc3cccc(c3)C(F)(F)F)C2=O)cc1
Target:
NOD-like Receptor (NLR); NOD

References

Zhang Y, Liu Y, Xie Z, et al.Inhibition of PFKFB Preserves Intestinal Barrier Function in Sepsis by Inhibiting NLRP3/GSDMD.Oxidative Medicine and Cellular Longevity.2022, 2022. Zhu Q, Zheng F, You W, et al.Expression of histone H1 in rats with traumatic brain injury and the effect of the NLRP3 inflammasome pathway.World Neurosurgery.2022 Jiang H, et al. Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders. J Exp Med. 2017 Nov 6;214(11):3219-3238. Jia Y, Cui R, Wang C, et al. Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway. Redox Biology. 2020: 101534. Jia Y, Cui R, Wang C, et al. Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway[J]. Redox Biology. 2020: 101534. Chen Z, Zhang S, Nie B, et al. Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway[J]. Redox Biology. 2020: 101534. Jia Y, Cui R, Wang C, et al. Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway. Redox Biology. 2020: 101534.