TargetMol

MTX-211

Product Code:
 
TAR-T4296
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4296-1mg1mg£148.00
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TAR-T4296-2mg2mg£205.00
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TAR-T4296-5mg5mg£333.00
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TAR-T4296-1mL1 mL * 10 mM (in DMSO)£338.00
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TAR-T4296-10mg10mg£470.00
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TAR-T4296-25mg25mg£728.00
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Quantity:
TAR-T4296-50mg50mg£978.00
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TAR-T4296-100mg100mg£1,299.00
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Quantity:
TAR-T4296-500mg500mg£2,456.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.
CAS:
1952236-05-3
Formula:
C20H14Cl2FN5O2S
Molecular Weight:
478.32
Pathway:
Tyrosine Kinase/Adaptors; JAK/STAT signaling; Angiogenesis; PI3K/Akt/mTOR signaling
Purity:
0.995
SMILES:
CS(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1
Target:
EGFR; PI3K

References

Small molecule inhibitors of egfr and pi3k. WO 2016100347 A2 Huang Y, Wang H, Hao Y, et al. Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity[J]. Nature Cell Biology. 2020: 1-12.?22-6 , 716?727? Huang Y, Wang H, Hao Y, et al. Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity. Nature Cell Biology. 2020: 1-12.?22-6 , 716?727?