TargetMol

SLV-2436

Product Code:
 
TAR-T4424
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4424-1mg1mg£130.00
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TAR-T4424-2mg2mg£157.00
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TAR-T4424-5mg5mg£213.00
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TAR-T4424-1mL1 mL * 10 mM (in DMSO)£230.00
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TAR-T4424-10mg10mg£303.00
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TAR-T4424-25mg25mg£513.00
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TAR-T4424-50mg50mg£707.00
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TAR-T4424-100mg100mg£946.00
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This product comes from: United States.
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Further Information

Bioactivity:
SLV-2436 (SEL201) is a novel effective and ATP-competitive inhibitor of MNK1 and MNK2 (IC50: 10.8/5.4 nM).
CAS:
2095704-43-9
Formula:
C19H15ClN4O
Molecular Weight:
350.8
Pathway:
MAPK
Purity:
0.9985
SMILES:
O=C1C=CC(=CN1CC=2C=CC=C(Cl)C2)C=3C=CC=4C(=NNC4C3)N
Target:
MNK

References

Zhan Y, Guo J, Yang W, et al. MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma.[J]. Journal of Clinical Investigation, 2017, 127(11):4179.