TargetMol

TA-01

Product Code:
 
TAR-T4645
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4645-1mg1mg£107.00
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TAR-T4645-2mg2mg£122.00
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TAR-T4645-5mg5mg£149.00
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TAR-T4645-1mL1 mL * 10 mM (in DMSO)£165.00
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TAR-T4645-10mg10mg£213.00
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TAR-T4645-25mg25mg£335.00
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TAR-T4645-50mg50mg£510.00
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TAR-T4645-100mg100mg£655.00
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Quantity:
TAR-T4645-500mg500mg£1,267.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.
CAS:
1784751-18-3
Formula:
C20H12F3N3
Molecular Weight:
351.332
Pathway:
Metabolism; Autophagy; MAPK; Stem Cells
Purity:
0.9994
SMILES:
Fc1ccc(cc1)-c1nc([nH]c1-c1ccncc1)-c1c(F)cccc1F
Target:
p38 MAPK; Casein Kinase; Autophagy

References

Laco F, et al. Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling. J Mol Cell Cardiol. 2015 Mar;80:56-70.