TargetMol

D-tetrahydropalmatine

Product Code:
 
TAR-T4S0779
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4S0779-1mg1mg£106.00
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TAR-T4S0779-5mg5mg£148.00
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TAR-T4S0779-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T4S0779-10mg10mg£203.00
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TAR-T4S0779-25mg25mg£327.00
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TAR-T4S0779-50mg50mg£455.00
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TAR-T4S0779-100mg100mg£623.00
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Further Information

Bioactivity:
D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor, it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes, and attenuate the viability reduction and LDH release of the primary cultured rat hepatocytes caused by MCT.
CAS:
3520-14-7
Formula:
C21H25NO4
Molecular Weight:
355.434
Pathway:
GPCR/G Protein; Neuroscience;
Purity:
0.9989
SMILES:
COc1cc2CCN3Cc4c(C[C@@H]3c2cc1OC)ccc(OC)c4OC
Target:
Dopamine Receptor

References

Tu M , Sun S , Wang K , et al. Organic cation transporter 1 mediates the uptake of monocrotaline and plays an important role in its hepatotoxicity[J]. Toxicology, 2013, 311(3):225-230.