TargetMol

AUT1

Product Code:
 
TAR-T5183
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5183-1mg1mg£103.00
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TAR-T5183-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T5183-5mg5mg£148.00
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TAR-T5183-10mg10mg£185.00
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TAR-T5183-25mg25mg£274.00
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TAR-T5183-50mg50mg£402.00
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TAR-T5183-100mg100mg£567.00
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Further Information

Bioactivity:
AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).
CAS:
1311136-84-1
Formula:
C18H19N3O4
Molecular Weight:
341.367
Pathway:
Membrane transporter/Ion channel
Purity:
0.9943
SMILES:
CC[C@H]1NC(=O)N(C1=O)c1ccc(Oc2ccc(C)c(OC)c2)nc1
Target:
Potassium Channel

References

Brown MR, et al. Physiological modulators of Kv3.1 channels adjust firing patterns of auditory brain stem neurons. J Neurophysiol. 2016 Jul 1;116(1):106-21. Rosato-Siri MD, et al. A Novel Modulator of Kv3 Potassium Channels Regulates the Firing of Parvalbumin-Positive Cortical Interneurons. J Pharmacol Exp Ther. 2015 Sep;354(3):251-60.