TargetMol

GS-443902

Product Code:
 
TAR-T5539
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5539-1mL1 mL * 10 mM (in DMSO)Enquire
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TAR-T5539-10mg10mgEnquire
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TAR-T5539-1mg1mgEnquire
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TAR-T5539-5mg5mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Remdesivir triphosphate is a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp) with IC50s of 1.1 ?M, 5 ?M for RSV RdRp and HCV RdRp, respectively. GS-443902 is the active triphosphate metabolite of Remdesivir.
CAS:
1355149-45-9
Formula:
C12H16N5O13P3
Molecular Weight:
531.203
Pathway:
Cell Cycle/Checkpoint; Metabolism; Proteases/Proteasome; DNA Damage/DNA Repair; Microbiology/Virology
Purity:
0.98
SMILES:
Nc1ncnn2c(ccc12)[C@@]1(O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O)C#N
Target:
Nucleoside Antimetabolite/Analog; HCV Protease; SARS-CoV; DNA/RNA Synthesis; RSV; Drug Metabolite

References

Pedersen N C , Perron M , Bannasch M , et al. Efficacy and safety of the nucleoside analog GS-441524 for treatment of cats with naturally occurring feline infectious peritonitis[J]. Journal of Feline Medicine & Surgery, 2019.