TargetMol

Ganoderic acid D

Product Code:
 
TAR-T5S1133
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T5S1133-25mg25mgEnquire
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TAR-T5S1133-10mg10mg£182.00
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Further Information

Bioactivity:
1. Ganoderic acid D is one of the major components in Ganoderma triterpenes. 2. Ganoderic acid D treatment for 48h inhibits the proliferation of HeLa human cervical carcinoma cells with an IC(5) value of 17.3 +/- .3 microM.
CAS:
108340-60-9
Formula:
C30H42O7
Molecular Weight:
514.659
Pathway:
DNA Damage/DNA Repair; Chromatin/Epigenetic; Apoptosis
Purity:
0.997
SMILES:
C[C@H](CC(=O)CC(C)C(O)=O)[C@H]1CC(=O)[C@@]2(C)C3=C(C(=O)C[C@]12C)[C@@]1(C)CCC(=O)C(C)(C)[C@@H]1C[C@@H]3O
Target:
Apoptosis; Sirtuin

References

Yue Q X , Cao Z W , Guan S H , et al. Proteomics Characterization of the Cytotoxicity Mechanism of Ganoderic Acid D and Computer-automated Estimation of the Possible Drug Target Network[J]. Molecular & Cellular Proteomics, 2008, 7(5):949-961. Shao C S, Zhou X H, Zheng X X, et al. Ganoderic acid D induces synergistic autophagic cell death except for apoptosis in ESCC cells. Journal of Ethnopharmacology. 2020, 262: 113213. Shao C S, Zhou X H, Zheng X X, et al. Ganoderic acid D induces synergistic autophagic cell death except for apoptosis in ESCC cells[J]. Journal of Ethnopharmacology. 2020, 262: 113213.